Over the last few decades, the concept of miniaturization has been actively explored for the development of more efficient analytical platforms. Besides microfluidic devices, a number of analytical platforms have emerged for high-throughput molecular measurements. Towards this goal, our group is dedicated to advancing the understanding and applicability of microfluidic devices, nanomaterials, and electrochemical processes. We are focused on the development of integrated analytical approaches that span from highly specialized instrumentation to simple paper-based devices. Applications of these projects include the quantification of biomedically-relevant analytes, the design of biocatalysts, and the implementation of artificial intelligence to address analytical problems.