Current projects

Electrochemical Biosensors

Simple and Efficient analytical tools
Staphylococcus aureus on the surface of a paper-derived carbon electrode, along with the electrodes and the portable instrument developed to quantify the Fe(CN)64- produced by the bacteria's metabolism.

Electrochemistry provides a simple, fast, and inexpensive way to quantify analytes at low concentrations and with tunable selectivity. Aiming to extend the applicability of ePADs, our group reported the possibility of implementing pyrolyzed paper as an active substrate for the development of detection electrodes. This material is produced via a simple manufacturing process and features competitive electrochemical activity, low cost, and the possibility to implement a wide variety of functionalization protocols. We are also interested in:

  • Development and integration of respirometric assays, as a way to detect metabolically-active bacteria
  • Wearable devices based on carbon electrodes modified with Au nanoparticles
  • Paper-based microfluidic devices (μPADs)
  • Our lab is also interested in the development of sensors based on other transduction methods, including optical

Recent papers

AI image of a drone that has a fishing line attached to it

Deployment of Solid-Supported NADES via Unmanned Aerial Vehicles to Preconcentrate Contaminants from Environmental Water Samples

Vagner B. dos Santos, Carlos D. Garcia, Helayne Santos, Vinicius Alcantra, Severino C. B. de Oliveira and Willian T. Saurez
ACS Omega 10 (2025) 48808–48817

Part of the Special Issue “Chemistry in Brazil: Advancing through Open Science

renato paper 02

Ultra-Dense Electrochemical Chips with Arrays of Nanostructured Microelectrodes to Enable Sensitive Diffusion-Limited Bioassays

Gabriel J. C. Pimentel, Lucas B. Ayres, Juliana N. Y. Costa, Waldemir J. Paschoalino, Kristi Whitehead, Lauro T. Kubota, Maria H. O. Piazzetta, Angelo L. Gobbi, Flávio M. Shimizu, Carlos D. Garcia, and Renato S. Lima
ACS Applied Materials & Interfaces 17 (2025) 13037–13049 (
cover article)

ChemistryPictures

ClemsonNews

2023 juliana

Au-Modified Carbon Electrodes Produced by Laser Scribing for Electrochemical Analysis of Probiotic Activity

Juliana L.M. Gongoni, George Chumanov, Thiago R.L.C. Paixão, and Carlos D. Garcia
Analysis & Sensing (2024) e202300056

vagner 2023

Lab-on-a-Drone: Remote voltammetric analysis of lead in water with real-time data transmission

João Paulo B. de Almeida, Vinicius de A. Carvalho, Leandro Paulo, Maysa L. do Nascimento, Severino B. de Oliveira, Willian T. Suarez, Carlos D. Garcia and Vagner B. dos Santos
Analytical Methods 15 (2023) 4827-4833 (cover article)

2023 review

Advancements and Future Directions in Cardiac Biomarker Detection Using Lateral Flow Assays

Stella S. da Silva, Mylena L. Cunha, Lucas B. Ayres, Carlos D. Garcia and Lucas Blanes
Analytical Methods 15 (2023) 3610 – 3630

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