Current projects

Food Antioxidants

Extending the lifetime of your food
Illustration of a lab and a whiteboard showing a scientific fact

Minimizing the oxidation of lipids remains one of the most important challenges to extend the shelf-life of food products and reduce food waste. While most consumer products contain antioxidants, the most efficient strategy is to incorporate combinations of two or more compounds, boosting the total antioxidant capacity. Unfortunately, the reasons for observing these effects in food samples are still unclear, and it is common to observe very different responses even for similar mixtures. Aiming to address this problem, we have developed several artificial intelligence models to predict synergistic interactions of antioxidant molecules. Outcomes of these projects will enable a more rational use of these molecules, providing safer alternatives to both producers and consumers. Thus, we are specifically interested in:

  • Understanding the chemical patterns and environmental factors that control the behavior of antioxidant mixtures 
  • Functional DES, made only with antioxidants, leading to mixtures that feature an increased total antioxidant capacity
  • In order to provide safer options, we aim to understand the interactions between natural molecules with antioxidant activity
  • Development of advanced tools for the quantification of antioxidants 

Recent papers

2025 dike 01

Functional Deep Eutectic Solvents to Boost Antioxidant Synergism in Edible Fats

Emmanuel Dike, Lucas Ayres, Tomas Benavidez, Jorge Barroso, Vagner dos Santos, and Carlos D. Garcia
ACS Sustainable Chemistry & Engineering 13 (2025) 4427–4438 (cover article)

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Deciphering Antioxidant Interactions via Data Mining and RDKit

Lucas B. Ayres, Justin T. Furgala, and Carlos D. Garcia
Scientific Reports 15 (2025) 670

 Authors acknowledge the support from the Open Access Publishing Fund

2023 juliana

Au-Modified Carbon Electrodes Produced by Laser Scribing for Electrochemical Analysis of Probiotic Activity

Juliana L.M. Gongoni, George Chumanov, Thiago R.L.C. Paixão, and Carlos D. Garcia
Analysis & Sensing (2024) e202300056

2023 09 GA

Predicting Antioxidant Synergism via Artificial Intelligence and Benchtop Data

Lucas B. Ayres, Tomás E. Benavidez, Armelle Varillas, Jeb R. Linton, Daniel C. Whitehead, and Carlos D. Garcia
J. of Agricultural and Food Chemistry 71 (2023) 15644–15655 (cover article)

checho cover

Removal of metals and inorganics from rendered fat using polyamine-modified cellulose nanocrystals

Ezequiel Vidal, Frank Alexis, José M Camiña, Carlos D. Garcia, and Daniel C. Whitehead
RSC Sustainability 1 (2023) 1184 – 1191

Cover article, featured in the 2024 RSC Fellows Collection

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