Biosketch:
Dr. Chris Chouinard received his Ph.D. in Analytical Chemistry from University of Florida in 2016, where he developed ion mobility-mass spectrometry methods for analysis of small biomolecules in complex samples. He then performed postdoctoral studies in development of Structures for Lossless Ion Manipulations (SLIM) at Pacific Northwest National Laboratory. After four years at Florida Tech, Chris joined Clemson in August 2022.

Research Summary:
Development of high-resolution ion mobility-mass spectrometry methods and technology for biomolecular characterization.

Research Group:
Dr. Chris Chouinard, Ralph Aderorho, Heidi Sabatini, Baker Garrison

Selected Publications:

1. Frank, C.L.; Jones, B.M.; Efird, E.; Hoover, M.; Kingsley, S.; Sabatini, H.M., Chouinard, C.D. “Profiling Multiple Steroid Subclasses Enabled by Rounded Turn SLIM Ion Mobility,” Journal of the American Society for Mass Spectrometry, 2025, 36, 2623-2632. Available from: https://pubs.acs.org/doi/full/10.1021/jasms.5c00218
2. Sabatini, H.M.; Pettit-Bacovin, T.; Aderorho, R.; Chouinard, C.D. “Multidimensional Separations for Characterization of Isomeric PFAS using SLIM High-Resolution Ion Mobility and Tandem Mass Spectrometry”, Analytical Chemistry, 2025, 97, 6727-6734. Available from: https://pubs.acs.org/doi/10.1021/acs.analchem.4c06985
3. Aderorho, R.; Chouinard, C.D. “Determining Protonation Site in Fentanyl Protomers using Ion Mobility-Aligned MS/MS Fragmentation,” International Journal of Mass Spectrometry, 2024, 496, 117185. Available from: https://www.sciencedirect.com/science/article/pii/S1387380623001768
4. Kingsley, S.; Hoover, M.; Pettit-Bacovin, T.; Sawyer, A.R.; Chouinard, C.D. “SLIM-based high-resolution ion mobility reveals new structural insights into isomeric vitamin D metabolites and their isotopologues,” Journal of the American Society for Mass Spectrometry, 2024, 35, 2650-2658. Available from: https://pubs.acs.org/doi/full/10.1021/jasms.4c00116
5. Neal, S.P.; Hodges, W.N.; Velosa, D.C.; Aderorho, R.; Lucas, S.W.; Chouinard, C.D. “Improved Analysis of Derivatized Steroid Hormone Isomers using Ion Mobility-Mass Spectrometry (IM-MS),” Analytical and Bioanalytical Chemistry, 2023, 415, 6757-6769. Available from: https://link.springer.com/article/10.1007/s00216-023-04953-8
6. Wedge, A.; Hoover, M.; Pettit-Bacovin, T.; Aderorho, R.; Efird, E.; Chouinard, C.D. “Development of a Rapid, Targeted LC-IM-MS Method for Anabolic Steroids,” Journal of the American Society for Mass Spectrometry, 2023, 34, 1708-1714. Available from: https://pubs.acs.org/doi/10.1021/jasms.3c00162