EPIC: At the forefront of biomedical research on eukaryotic pathogens

EPIC: At the forefront of biomedical research on eukaryotic pathogens

epic home pic

Eukaryotic pathogens cause some of the most devastating and intractable diseases in humans, including malaria, amoebic dysentery, sleeping sickness, Chagas disease and fungal meningitis. Globalization has increased such infections in the U.S. Many eukaryotic pathogens are classified as bioterrorism agents and/or neglected tropical diseases.

Clemson University’s Eukaryotic Pathogens Innovation Center — EPIC — is an interdisciplinary research cooperative founded in 2013 that is at the forefront of biomedical research on these devastating pathogens.

EPIC scientists have a lengthy track record of major contributions in this globally important area of research.


Congratulations to Dr. Kim Paul on the publishing of her article about Guinea worms in The Conversation!

Read the article here: https://theconversation.com/guinea-worm-a-nasty-parasite-is-nearly-eradicated-but-the-push-for-zero-cases-will-require-patience-199156


Congratulations to Dr. Jim Morris on his recent grant!

Dr. Jim Morris received a two year NIH award of $419k, which will support the development of genetic tools to study the brain-eating amoebae.

Project Name: Approaches for genetic manipulation of Naegleria fowleri

Project Number: NIH R21AI175463


Congratulations to Dr. Lukasz Kozubowski on his two recent grants!


Dr. Lukasz Kozubowski (co-PI) in collaboration with Dr. Julia Brumaghim from the Department of Chemistry (PI) received an NSF award of $492k split between their two laboratories to study the mechanisms that lead to the development of resistance to azole drugs in Cryptococcus neoformans.

Project Name: Azole Antifungals Coordinate Metals and Create Reactive Oxygen Species That Damage DNA and Cause Chromosomal Instability

PAward Number (FAIN): 2203847



The National Institute Of Allergy And Infectious Diseases awarded Dr. Lukasz Kozubowski a five-year grant of ~$1.9 total amount for 5 years to focus on a fungal infection associated with HIV/AIDS. The study will help to identify safer and more effective drugs that target cryptococcal infections like the life-threatening meningo-encephalitis in an immunocompromised host.

Project Name: The role of septins in the adaptation of Cryptococcus neoformans to host temperature in HIV-based cryptococcosis

Project Number: 1R01AI167692-01A1



For further information about the EPIC please contact us.

864-656-EPIC or clemson_epic@clemson.edu