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Development of a cyclic ion mobility spectrometry-mass spectrometry-based collision cross-section database of permethylated human milk oligosaccharides

Development of a cyclic ion mobility spectrometry-mass spectrometry-based collision cross-section database of permethylated human milk oligosaccharides Sanaz C. Habibi, Victoria R. Bradford, Sophie C. Baird, Shadrack Wilson Lucas, Christopher D. Chouinard, and Gabe Nagy* J. Mass Spectrom. 2024, 59, 8, e5076 Publication Date: July 23, 2024 https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/jms.5076 Human milk oligosaccharides (HMOs) are an important class of biomolecules…

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Meet the PI: Dr. Christopher D. Chouinard

Dr. Christopher D. Chouinard, Assistant Professor Dr. Chouinard was born and raised in the small town of Grafton, MA. His interests in chemistry and biology brought him south, where he attended University of North Carolina at Chapel Hill (Go Tar Heels!) and furthered his passion for analytical chemistry. After briefly working as a project manager…

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Three Undergrads Honored at Chemistry Departmental Awards Ceremony

Three Undergrads Honored at Chemistry Departmental Awards Ceremony On Friday, April 12th, the Clemson Chemistry Department hosted its annual Honors and Awards Event. The Chouinard Group was well represented, with three undergrad students taking home well-deserved awards! Undergraduate Awards in Analytical Chemistry: Copeland Johnson Chemistry Faculty Award: Walker Hodges Warwick Chemical Foundation Award in Chemistry: Breland Jones Congratulations…

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IM-MS Measurement of Anabolic Steroids and Other Performance-Enhancing Drugs for Anti-Doping Applications

Mass spectrometry has been the technique of choice in anti-doping labs since the Los Angeles Olympic Games in 1984. Since then, a combination of targeted tandem mass spectrometry and high-resolution techniques have been used to quantify and identify anabolic steroids and other performance-enhancing drugs, respectively. Recently, the promise of ion mobility-mass spectrometry (IM-MS) has been…

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Walker Hodges Named College of Science “Outstanding Undergraduate in Discovery”

Walker Hodges Named College of Science “Outstanding Undergraduate in Discovery” Walker Hodges, a chemistry major in the Chouinard Research Group, has established himself as a leader in the reactions subgroup performing reactions on different isomeric compounds. One application of this research is to help provide analysis for organizations like the World Anti-Doping Agency to prevent…

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Chemical Reactions and Noncovalent Complexes as Ion Mobility ‘Shift Reagents’

Where the resolving power of IM-MS techniques is insufficient to differentiate challenging isomers, various chemical approaches have been used to alter their mobility with the goal of better separations. We are primarily focused on simple, fast, and inexpensive reactions targeting common steroid functional groups. Thus far, we have published on reactions with ozone, simple carbonyls…