CHG Research Cores
CHG Research Cores
The Center for Human Genetics houses two Research Cores, the Genomic Core and the Bioinformatics and Statistics Core. The Genomics Core offers state-of-the-art infrastructure for high-throughput sequencing and molecular biology workflows. The Bioinformatics and Statistics Core delivers powerful computational support and expert analysis to accelerate data-driven discovery. Together, the Cores provide a start to finish next generation sequencing pipeline.
Our Center houses various equipment for almost any NGS need including but not limited to:
- Illumina NovaSeq X+
- PacBio Revio
- ONT PromethION P2 Integrated
- 10X Genomics Chromium iX
- Qubit
- TapeStation
- Fragment Analyzer
- Nanodrop
- Illumina Single Cell Starter Kit
- Covaris Focused-Ultrasonicator
Our Center also houses an in-house DELL EMC Cluster with the following capabilities for rapid and high-throughput analysis:
- 14 General Purpose Compute Nodes with 40 – 96 cores and 192GB – 1TB RAM
- 10 Big Memory Nodes with 40 – 128 cores and 1.5TB – 4TB RAM
- 6 Interactive Nodes with 28 – 32 cores and 128GB – 256GB RAM
- 2 GPU Nodes with 2 x H100 192GB GPUs
- 1 GPU Node with 2 x L40S 48GB GPUs
- 1 DGX Node with 8 x A100 80GB GPUs
- 1.25PB of RAID6 XFS storage
- 214TB of Solid State storage
🧬 Workshops and Retreats 🧬
Expand your molecular and computational biology skills with our expert-led training sessions
Bioinformatics
Genomics
💻 High Performance Computing (HPC) Basics - Fall/Spring
This workshop includes many items discussed in the Secretariat Documentation and will help you use Secretariat, the CHG HPC, effectively. We recommend that all Secretariat users attend this workshop.
🔧 Git & GitHub - Fall/Spring
This workshop assumes no prior knowledge of Git or GitHub. It will include an introduction to common Git commands and use cases in addition to best practices for using GitHub for collaborative projects.
🧬 RNA-Seq Retreat - Summer
Attendees will learn about transcriptomic analysis through a series of lectures, demonstrations, and hands-on activities. No laboratory work will be conducted, only discussed. Topics will range from experimental design, quality control, alignment, feature counting, and normalization to enrichment and association analysis.
🔬 DNA and RNA QC Seminar - Fall
Master quality control techniques for nucleic acid samples. Learn to assess sample integrity, quantification methods, and troubleshoot common QC issues.
🥼 Hands-On Wet Lab Workshops - Variable
These workshops will cover a variety of workflows from short read sequencing (both RNA and WGS) and long read sequencing. These workshops allow participants to get hands-on experience making their own libraries using test samples.
📊 Short Read vs Long Read: Which is Best for Your Project - Coming Soon
Compare sequencing technologies and learn to choose the optimal approach for your research goals. Covers cost analysis, data quality considerations, and application-specific recommendations.
🔍 Library QC and Sequencing - Coming Soon
Seminar Comprehensive guide to library preparation quality control and sequencing optimization. Learn best practices for library validation, troubleshooting failed libraries, and maximizing sequencing efficiency.
Joint Bioinformatics & Genomics
🧪 Single Cell Sequencing - Coming Fall
This workshop will cover both the molecular and bioinformatic workflow for single cell sequencing. Beginning with experimental design and getting a good starting sample to library preparation and then to in depth data analysis and interoperation. Attendees will gain an understanding of cutting-edge single cell technologies.
Connect with Our Cores
Ready to elevate your research? Contact the Clemson Center for Human Genetics Research Cores today to learn more about our Genomics and Bioinformatics Cores. Our team is eager to assist you with your research needs and provide expert guidance. Schedule a consultation to explore how we can support your scientific endeavors.
In order to work with the research cores and utilize our equipment, you must sign our acknowledgement policy. Please view it below and contact us if you’d like to sign.
Questions?
For further information about the Clemson Center for Human Genetics please contact us.
or
chg@clemson.edu