This project aimed to provide an experience to transform the perception of undergraduates from that of students to that of active researchers. To accomplish this, REU students in our program performed research in projects linked to Materials with Targeted Functions: from fundamentals to applications. The selected areas allowed exposing participants to a broad research experience across disciplines and to take advantage of the concept of cluster mentoring. As a new element, also steaming from comments from past participants, the program also targeted social competencies. This program is directed by Drs. Carlos D. Garcia, Bill Pennington, and Tania I. Houjeiry (Coordinator). The REU program will provide financial support to cover travel expenses (flight to GSP and ground transportation to Clemson), on-campus housing, meals, and a $5,500 scholarship. The REU grant will not pay for any other expense outside the scope of the sponsored activity. This program was financed by the NSF – Division of Chemistry, award CHE-2050042 (2021-2024) and is now closed. Participation of students from the SC Governor’s School for Science and Mathematics (during the summer of 2022) was supported by NSF – Division of Chemistry, award CHE-2227374.
Publications by Participants
Profiling Multiple Steroid Subclasses Enabled by Rounded Turn SLIM Ion Mobility
Cole L. Frank, Breland M. Jones, Emmaleigh Efird, Makenna Hoover, Selena Kingsley, Heidi M. Sabatini, and Christopher D. Chouinard
J. Am. Soc. Mass Spectrom. (2025) – in press
Diazacyclobutenes as Reactive Intermediates: The Cascade Cyclization of Thiolated Ene-ynes and Azodicarboxylates to Provide Tetrahydroindoles
Samuel Kwain, Chandima J. Narangoda, Brock A. Miller, William DeSnoo, Monireh Noori, James W. D. Morris, Lauren Ulisse, Robert L. Stevenson III, Colin D. McMillen, Rakesh Sachdeva, Dean J. Tantillo, and Daniel C. Whitehead
J. Org. Chem. 90 (2025) 7417–7427
Enantioselective Deoxygenative Amino-Cyanation of Carboxylic Acids via Ti-Multicatalysis
Giovani Gutierrez, Jason A. Wilt, Samirah Muhammad, Emily Girotti, Diego Rodriguez, Byoungmoo Kim
Org. Lett. 26 (2024) 9442–9447
Ammonium-Binding Bifunctional Aza-Crown Ether Catalysts for Substrate-Selective Hydroxyl Functionalization
Austin G. Seilkop, Amaechi S. Odoh, Nicholas J. Coradi, Jacob I. Wright, Jorge Barroso, Byoungmoo Kim
J. Org. Chem. 89 (2024) 13338–13344
SuFEx-Enabled Direct Deoxy-Diversification of Alcohols
Amaechi Shedrack Odoh, Courtney Keeler, and Byoungmoo Kim*
Org. Lett. 26 (2024) 4013–4017
SLIM-Based High-Resolution Ion Mobility Reveals New Structural Insights into Isomeric Vitamin D Metabolites and their Isotopologues
Selena Kingsley, Makenna Hoover, Terra Pettit-Bacovin, Anna Rose Sawyer, Christopher Chouinard
J. Am. Soc. Mass Spectrom. 35 (2024) 2650–2658
Big Data for a Deep Problem: Understanding the Formation of NADES Through Comprehensive Chemical Analysis and RDKit
Lucas B. Ayres, Grayson Weavil, Mays Alhoubani, Barbara G. S. Guinati, and Carlos D. Garcia
Journal of Molecular Liquids 389 (2023) 122891
Predicting Antioxidant Synergism via Artificial Intelligence and Benchtop Data
Lucas B. Ayres, Tomás E. Benavidez, Armelle Varillas, Jeb R. Linton, Daniel C. Whitehead, and Carlos D. Garcia
J. of Agricultural and Food Chemistry 71 (2023) 15644–15655 (cover article)
Rapid Detection of Staphylococcus aureus Using Paper-Derived Electrochemical Biosensors
Lucas Ayres, Jordan Brooks, Kristi Whitehead, Carlos D Garcia
Analytical Chemistry 94 (2022) 16847–16854 (cover article)








