Research Experience for Undergraduates

IMPRESS: IMPlanting the ResEarch Seed in Students

This project aimed to provide an experience to transform the perception of undergraduates from that of students to that of active researchers. To accomplish this, REU students in our program performed research in projects linked to Materials with Targeted Functions: from fundamentals to applications. The selected areas allowed exposing participants to a broad research experience across disciplines and to take advantage of the concept of cluster mentoring. As a new element, also steaming from comments from past participants, the program also targeted social competencies. This program is directed by Drs. Carlos D. GarciaBill Pennington, and Tania I. Houjeiry (Coordinator). The REU program will provide financial support to cover travel expenses (flight to GSP and ground transportation to Clemson), on-campus housing, meals, and a $5,500 scholarship. The REU grant will not pay for any other expense outside the scope of the sponsored activity. This program was financed by the NSF – Division of Chemistry, award CHE-2050042 (2021-2024) and is now closed. Participation of students from the SC Governor’s School for Science and Mathematics (during the summer of 2022) was supported by NSF – Division of Chemistry, award CHE-2227374.

Publications by Participants

Image showing two peaks and a molecule

Profiling Multiple Steroid Subclasses Enabled by Rounded Turn SLIM Ion Mobility

Cole L. Frank, Breland M. Jones, Emmaleigh Efird, Makenna Hoover, Selena Kingsley, Heidi M. Sabatini, and Christopher D. Chouinard
J. Am. Soc. Mass Spectrom. (2025) – in press

Picture of a chemical reaction

Diazacyclobutenes as Reactive Intermediates: The Cascade Cyclization of Thiolated Ene-ynes and Azodicarboxylates to Provide Tetrahydroindoles

Samuel Kwain, Chandima J. Narangoda, Brock A. Miller, William DeSnoo, Monireh Noori, James W. D. Morris, Lauren Ulisse, Robert L. Stevenson III, Colin D. McMillen, Rakesh Sachdeva, Dean J. Tantillo, and Daniel C. Whitehead
J. Org. Chem. 90 (2025) 7417–7427

2024 Boni

Enantioselective Deoxygenative Amino-Cyanation of Carboxylic Acids via Ti-Multicatalysis

Giovani Gutierrez, Jason A. Wilt, Samirah Muhammad, Emily Girotti, Diego Rodriguez, Byoungmoo Kim
Org. Lett. 26 (2024) 9442–9447

Picture1

Ammonium-Binding Bifunctional Aza-Crown Ether Catalysts for Substrate-Selective Hydroxyl Functionalization

Austin G. Seilkop, Amaechi S. Odoh, Nicholas J. Coradi, Jacob I. Wright, Jorge Barroso, Byoungmoo Kim
J. Org. Chem. 89 (2024) 13338–13344

2024 keeler

SuFEx-Enabled Direct Deoxy-Diversification of Alcohols

Amaechi Shedrack Odoh, Courtney Keeler, and Byoungmoo Kim*
Org. Lett. 26 (2024) 4013–4017

2024 selena

SLIM-Based High-Resolution Ion Mobility Reveals New Structural Insights into Isomeric Vitamin D Metabolites and their Isotopologues

Selena Kingsley, Makenna Hoover, Terra Pettit-Bacovin, Anna Rose Sawyer, Christopher Chouinard
J. Am. Soc. Mass Spectrom. 35 (2024) 2650–2658

2023 RDKit

Big Data for a Deep Problem: Understanding the Formation of NADES Through Comprehensive Chemical Analysis and RDKit

Lucas B. Ayres, Grayson Weavil, Mays Alhoubani, Barbara G. S. Guinati, and Carlos D. Garcia
Journal of Molecular Liquids 389 (2023) 122891

2023 09 GA

Predicting Antioxidant Synergism via Artificial Intelligence and Benchtop Data

Lucas B. Ayres, Tomás E. Benavidez, Armelle Varillas, Jeb R. Linton, Daniel C. Whitehead, and Carlos D. Garcia
J. of Agricultural and Food Chemistry 71 (2023) 15644–15655 (cover article)

lucas staph

Rapid Detection of Staphylococcus aureus Using Paper-Derived Electrochemical Biosensors

Lucas Ayres, Jordan Brooks, Kristi Whitehead, Carlos D Garcia
Analytical Chemistry 94 (2022) 16847–16854 (cover article)

ClemsonNews

Top