Graduate Student
Email: monirem@clemson.edu
Monireh Mohammadpanah
Biosketch
Monireh obtained her Bachelor degree in Cellular and Molecular Biology from Chamran University and Master degree in Molecular Genetics from Yazd University in Iran. Her research focused on epigenetic regulation of atherosclerosis-associated gene promoters. She then joined an Internship program in Meybod Genetic Research Center where she studied miRNAs expression in human neurologic disorders. In 2020, she joined Medical Nanotechnology and Tissue Engineering Research Center as a research assistant to improve nanoparticle drug delivery in breast cancer.
Research
In January 2022, she joined the lab of Dr. Andrei Alexandrov at the Clemson Center for Human Genetics as a doctoral student. Her research focuses on the validation of factors regulating human metastasis-associated long non-coding RNA MALAT1 and the development of ultra-high throughput functional screening technology to map potential druggable sites within multi-functional essential human proteins. Her second project studies the pathway of nonsense-mediated mRNA degradation that is involved in hundreds of human genetic disorders.
Publications
Identification of Human Pathways Acting on Nuclear Non-Coding RNAs Using the Mirror Forward Genetic Approach. Nature Communications, 2025. https://doi.org/10.1038/s41467-025-59998-3
Identification of RMP24 and RMP64, Human Ribonuclease MRP-Specific Protein Components. Cell Reports, 2025. https://doi.org/10.1016/j.celrep.2025.115752
Identification of Pathway-Specific Surfaces in the Human RNA Exosome Using Deep Mutational Scanning. Eukaryotic mRNA Processing, CSHL, 2025 — Poster presentation.
Identification of Pathway-Specific Surfaces in the Human RNA Exosome Using Deep Mutational Scanning. RNA Society Annual Meeting, San Diego, 2025 — Poster presentation.
Bacteria-Free Approach for Expressing Nucleic Acids and Proteins in Eukaryotic Cells. U.S. Patent Application US20250163437A1, 2024. https://patents.google.com/patent/US20250163437A1/en