Islet amyloid polypeptide fibril catalyzes amyloid-β aggregation by promoting fibril nucleation rather than direct axial growth by Zhiyuan Song
Zhiyuan is a 6th-year graduate student working with his advisor, Dr. Feng Ding, in Biophysics.. Check out his paper here. “Proteins like amyloid-beta (Aβ) and islet amyloid polypeptide (IAPP) can misfold and form structures called amyloid fibrils, which are linked to diseases like Alzheimer’s (AD) and type 2 diabetes (T2D). We used physics-based molecular dynamics […]