Interaction of Macromolecules with Nanostructred Materials

The adsorption of proteins to surfaces is a central concern for the rational design and application of materials. The rate and strengths of the initial physical interactions between proteins and surfaces dictate (to a large degree) the final conformation, stability, and activity of such proteins. This issue, that plays a major role in determining the biocompatibility of materials, can also dictate the analytical performance of almost every analytical device that uses a biorecognition element (antigen, antibody, enzyme, nucleic acids, or even whole cells). Here are described several of the project that we have recently published in this area.

Analytical Issues linked to the Adsorption of Proteins
Effect of External Potential on the Adsorption of Proteins