Dependency of fentanyl analogue protomer ratios on solvent conditions as measured by ion mobility-mass spectrometry Copeland R. Johnson, Heidi M. Sabatini, Ralph Aderorho, and Christopher D. Chouinard* J. Mass Spectrom. 2024, 59, 8, e5070 Publication Date: July 11, 2024 https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/jms.5070 Recently, our group has shown that fentanyl and many of its analogues form prototropic isomers (“protomers”) during…

SLIM-Based High-Resolution Ion Mobility Reveals New Structural Insights into Isomeric Vitamin D Metabolites and their Isotopologues Selena Kingsley, Makenna Hoover, Terra Pettit-Bacovin, Anna Rose Sawyer, and Christopher D. Chouinard* J. Amer. Soc. Mass Spectrom. 2024, 35, 11, 2650-2658 Publication Date: May 6, 2024 https://pubs.acs.org/doi/full/10.1021/jasms.4c00116 Testing for vitamin D deficiency remains a high-volume clinical assay, much of which…

Rapid differentiation of xylazine metabolites using SLIM IM-MS Ralph Aderorho, Shadrack Wilson Lucas, and Christopher D. Chouinard* Anal. Methods. 2024, 16, 4041-4044 Publication Date: June 5, 2024 https://pubs.rsc.org/en/content/articlehtml/2024/ay/d4ay00801d Xylazine represents an increased threat to the recreational drug market. In this study, we present a rapid strategy for identifying xylazine and differentiating its common isomeric metabolites using Structures…