Agilent 6545 QTOF LC-MS/MS Mass Spectrometer

Mass range – 50-10,000 m/z

Dynamic range : 5 orders of magnitude

Resolving power : 45,000 FWHM at m/z 2722

RMS :   0.8 ppm at (M+H)+ ion m/z 609.2807 (reserpine) in MS mode

better than 2 ppm RMS on m/z 397 of reserpine in MS/MS mode.

Spectral acquisition rate :

MS mode – 50 spectra/second (m/z 50 to 1700 with   resolution of 40,000 at m/z 2722 in 4 GHz mode.

MS/ MS mode – 30 spectra/second (m/z 50 to 1700   with resolution of 40,000 at m/z 2722 in 4 GHz mode.

Agilent 1290 Quaternary pump HPLC

Maximum operating pressure – 800bar

Flow rates – upto 5ml/min

Column compartment – Peltier-element (20 degrees below ambient to 110 °C

Autosampler –   operating range 4oC – 40oC

capacity of 132 vials

Diode array detector : programmable slit width, 1,2, 4, 8, 16nm. Up to 8 specific wavelengths in the wavelength range 190-950nm, settable in 1 nm increments.

LC-MS/MS QTOF

Location: Hunter 241A