{"id":14290,"date":"2025-05-15T13:32:46","date_gmt":"2025-05-15T13:32:46","guid":{"rendered":"https:\/\/scienceweb.clemson.edu\/uacl\/?p=14290"},"modified":"2025-11-06T01:52:44","modified_gmt":"2025-11-06T01:52:44","slug":"reu-mentors","status":"publish","type":"post","link":"https:\/\/scienceweb.clemson.edu\/uacl\/reu-mentors\/","title":{"rendered":"DESSA: Mentors and Projects"},"content":{"rendered":"\t\t
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A unique aspect of the proposed program is prioritizing a cohesive research experience for the participants, who will be mentored by experts in the field of DES. One unique aspect of these solvents is that the structure of the selected components provides a versatile platform to adjust their properties, potentially enabling the design of DES towards specific applications. Despite recent advances, the rational design of DES remains elusive, and most undergraduate students are not even aware of their existence. Aiming to address gaps in both training and knowledge, this program offers participants a range of projects linked to DES, covering not only the synthesis but also a wide range of applications, from machine learning to environmental remediation and drug delivery. These projects have been designed taking into account the constraints of a ten-week research experience and considering groups of two participants.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\"REU<\/a><\/div>\n

DES Properties via Machine Learning<\/a><\/h4>
We have recently demonstrated the utility of AI (Transformer-Based Model) to predict the formation of multiple, new, and stable DES (n=337) from a general database of natural compounds. We have also expanded these studies to more complex models, leading to predictions of the melting point of DES with an average ...<\/div><\/div><\/div>\n
\"REU<\/a><\/div>\n

X-panded polyiodides and DES<\/a><\/h4>
While most DES are formed by hydrogen bonding,\u00a0Pennington\u2019s group recently observed that grinding 1,3-dithiane with 1,2-F4DIB resulted in the formation of the first reported DES formed by halogen bonding (XB). This strong and highly directional interaction can be exploited to develop supramolecular synthons for rational crystal design and materials development ...<\/div><\/div><\/div>\n
\"REU<\/a><\/div>\n

Stability of H-Bonding in Aqueous Mixtures of NADES<\/a><\/h4>
Most reported NADES are highly viscous at room temperature, a characteristic that is attributed to the formation of the hydrogen bonding network among their components and that represents the most pressing obstacle for their implementation in a wide variety of fields. Although different strategies have been presented to overcome this ...<\/div><\/div><\/div>\n
\"REU<\/a><\/div>\n

Light emitting materials based on chiral DES<\/a><\/h4>
This research aims to develop and characterize circularly polarized light-emitting materials based on chiral DES that are solvents for luminescent lanthanide complexes. Recent work has demonstrated that chiral DES (incorporating at least one chiral component) can induce circularly polarized luminescence (CPL) from luminescent lanthanide (europium and terbium) complexes. These results ...<\/div><\/div><\/div>\n
\"REU<\/a><\/div>\n

Interaction of DES with cells<\/a><\/h4>
The vast majority (>99%) of the injected nanoparticles do not reach their intended destination, which hampers their clinical application. Addressing this problem, the Tanner lab has recently demonstrated that specific choline-based DES can direct preferential accumulation in certain tissues while others can promote transdermal transport or even hitchhike onto blood ...<\/div><\/div><\/div>\n
\"REU<\/a><\/div>\n

DES for Wood Pulping<\/a><\/h4>
Characterized by low vapor pressure and ease of preparation, DES offer an adaptable platform wherein physicochemical properties such as acidity and polarity can be finely tuned to suit specific applications. Atilhan\u2019s lab has explored these properties toward the delignification of wood chips with a moisture content of 50%, at low ...<\/div><\/div><\/div>\n
\"REU<\/a><\/div>\n

Activity of NADES at the Multiomic Level<\/a><\/h4>
Due to improved biocompatibility, natural deep eutectic solvents (NADES) are increasingly explored in biomedicine.93 Yet, our understanding of how they interact with biomolecules at multiomic levels- metabolome, proteome, epigenome, and transcriptome - remains poor. Recently, Agatemor\u2019s group found that a NADES designed from choline and geranic acid (CAGE) upregulates indole-3-lactic ...<\/div><\/div><\/div>\n
\"REU<\/a><\/div>\n

DES for the Extraction of Contaminants<\/a><\/h4>
GUMBOS are solid-phase organic salts with melting points ranging from 25\u00b0C to 250\u00b0C that are particularly valuable in multiple aspects of the analytical workflow. For example, the hydrophobicity of GUMBOS can be adjusted by modifying the counterion or by incorporating nanomaterials through a simple reprecipitation method in water.\u00a0Participants involved in ...<\/div><\/div><\/div>\n
\"REU<\/a><\/div>\n

DES Deconstruction of Sweet Potato Vines to Separate Lignin<\/a><\/h4>
Separating lignin from cellulose in biomass is a necessary pretreatment step prior to converting them to biofuels or bioproducts. If byproducts from food production can be separated in an ecofriendly solvent at low pressures, biomass specifically grown for biorefining will not need to be shipped long distances. Thus, this project ...<\/div><\/div><\/div>\n
\"REU<\/a><\/div>\n

Adsorption of PFAS onto DES<\/a><\/h4>
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are a diverse class of synthetic fluorinated organic substances that have been used in numerous industrial and commercial applications since the 1950s. Due to the extensive utilization of PFAS and subsequent release into the environment, a wide variety of these substances have been identified in ...<\/div><\/div><\/div><\/div><\/div> <\/div> \t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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A unique aspect of the proposed program is prioritizing a cohesive research experience for the participants, who will be mentored by experts in the field of DES. One unique aspect of these solvents is that the structure of the selected components provides a versatile platform to adjust their properties, potentially enabling the design of DES towards specific applications. Despite recent advances, the rational design of DES remains elusive, and most undergraduate students are not even aware of their existence. Aiming to address gaps in both training and knowledge, this program offers participants a range of projects linked to DES, covering […]<\/p>\n","protected":false},"author":20,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[183],"tags":[],"class_list":["post-14290","post","type-post","status-publish","format-standard","hentry","category-reu"],"yoast_head":"\nDESSA: Mentors and Projects - Microanalytical Chemistry Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/scienceweb.clemson.edu\/uacl\/reu-mentors\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"DESSA: Mentors and Projects - Microanalytical Chemistry Lab\" \/>\n<meta property=\"og:description\" content=\"A unique aspect of the proposed program is prioritizing a cohesive research experience for the participants, who will be mentored by experts in the field of DES. 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