1.0Microanalytical Chemistry Labhttps://scienceweb.clemson.edu/uaclCDGhttps://scienceweb.clemson.edu/uacl/author/carlos/rich600338<blockquote class="wp-embedded-content" data-secret="xRmrxRHcCQ"><a href="https://scienceweb.clemson.edu/uacl/interaction-of-des-with-cells/">Interaction of DES with cells</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://scienceweb.clemson.edu/uacl/interaction-of-des-with-cells/embed/#?secret=xRmrxRHcCQ" width="600" height="338" title="“Interaction of DES with cells” — Microanalytical Chemistry Lab" data-secret="xRmrxRHcCQ" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script> /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=https://scienceweb.clemson.edu/uacl/wp-includes/js/wp-embed.min.js </script> https://scienceweb.clemson.edu/uacl/wp-content/uploads/sites/46/2025/04/REU_project_05.png750775The vast majority (>99%) of the injected nanoparticles do not reach their intended destination, which hampers their clinical application. Addressing this problem, the Tanner lab has recently demonstrated that specific choline-based DES can direct preferential accumulation in certain tissues while others can promote transdermal transport or even hitchhike onto blood cells. Considering her unique expertise, REU participants will be tasked with unveiling the role of DES in drug delivery, following the hypothesis that such interactions depend on the chemical properties of the components selected to build the DES. Thus, participants will first synthesize a library of DES based on choline and […]