{"id":634,"date":"2019-10-15T09:54:07","date_gmt":"2019-10-15T13:54:07","guid":{"rendered":"https:\/\/scienceweb.clemson.edu\/chg\/?p=634"},"modified":"2025-07-30T10:20:17","modified_gmt":"2025-07-30T14:20:17","slug":"dr-jennifer-mason","status":"publish","type":"post","link":"https:\/\/scienceweb.clemson.edu\/ihg\/dr-jennifer-mason\/","title":{"rendered":"Dr. Jennifer Mason"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;section&#8221; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row admin_label=&#8221;row&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text admin_label=&#8221;Text&#8221; _builder_version=&#8221;4.27.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p class=\"et_pb_member_position\"><strong>Assistant Professor, Department of Genetics and Biochemistry<\/strong><\/p>\n<p>Email: jmason4@clemson.edu<br \/>Phone: 864-656-3345<\/p>\n<h2><strong>Biosketch<\/strong><\/h2>\n<p><img fetchpriority=\"high\" fetchpriority=\"high\" decoding=\"async\" class=\"size-medium wp-image-635 alignright\" src=\"https:\/\/scienceweb.clemson.edu\/chg\/wp-content\/uploads\/sites\/4\/2019\/10\/chg-jennifer-mason_IMG_8014-240x300.jpg\" alt=\"\" width=\"240\" height=\"300\" srcset=\"https:\/\/scienceweb.clemson.edu\/ihg\/wp-content\/uploads\/sites\/4\/2019\/10\/chg-jennifer-mason_IMG_8014-240x300.jpg 240w, https:\/\/scienceweb.clemson.edu\/ihg\/wp-content\/uploads\/sites\/4\/2019\/10\/chg-jennifer-mason_IMG_8014-768x960.jpg 768w, https:\/\/scienceweb.clemson.edu\/ihg\/wp-content\/uploads\/sites\/4\/2019\/10\/chg-jennifer-mason_IMG_8014-819x1024.jpg 819w, https:\/\/scienceweb.clemson.edu\/ihg\/wp-content\/uploads\/sites\/4\/2019\/10\/chg-jennifer-mason_IMG_8014-1080x1350.jpg 1080w, https:\/\/scienceweb.clemson.edu\/ihg\/wp-content\/uploads\/sites\/4\/2019\/10\/chg-jennifer-mason_IMG_8014.jpg 1200w\" sizes=\"(max-width: 240px) 100vw, 240px\" \/><\/p>\n<p>I received by B.Sc. from Central Michigan University (Mt. Pleasant, MI) and my Ph.D. in Human Genetics from the University of Michigan (Ann Arbor, MI). I joined Clemson University as an assistant professor in the department of Genetics and Biochemistry in January 2017.<\/p>\n<h2><strong>Research<\/strong><\/h2>\n<p>Our lab is interested in understanding the molecular mechanisms underlying genome instability in human cancers. Specifically, we study the role of the DNA repair pathway, homologous recombination, in repair of DNA damage caused by double strand break inducing chemotherapeutics and replication stress. This pathway prevents the accumulation of potentially detrimental mutations and protects genome stability. In addition, we are aiming to understand how DNA repair pathways function to protect replication forks in response to genotoxic stresses.\u00a0 Finally, we are interested in identifying and characterizing genetic interactions that may lead to novel chemotherapeutic treatments for cancers harboring defects in DNA repair pathways.<\/p>\n<h2><strong>Publications<\/strong><\/h2>\n<p>Abrams SR, Hawks AL, Evans JM, Famula TR, Mahaffey M, Johnson GS, <strong>Mason JM<\/strong> and <strong>Clark LA<\/strong>. 2020. Variants in\u00a0<em>FtsJ RNA 2&#8242;-O-Methyltransferase 3<\/em>\u00a0and\u00a0<em>Growth Hormone 1<\/em>\u00a0are associated with small body size and a dental anomaly in dogs. <em>Proc Natl Acad Sci USA.<\/em> <strong>117:<\/strong> 24929-24935. doi: 10.1073\/pnas.2009500117.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Director<\/p>\n","protected":false},"author":4,"featured_media":635,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p class=\"et_pb_member_position\"><strong>Assistant Professor, Department of Genetics and Biochemistry<\/strong><\/p>\r\nEmail: jmason4@clemson.edu\r\nPhone: 864-656-3345\r\n<h3><strong>Biosketch<\/strong><\/h3>\r\n<img class=\"size-medium wp-image-635 alignright\" src=\"https:\/\/scienceweb.clemson.edu\/chg\/wp-content\/uploads\/sites\/4\/2019\/10\/chg-jennifer-mason_IMG_8014-240x300.jpg\" alt=\"\" width=\"240\" height=\"300\" \/>\r\n\r\nI received by B.Sc. from Central Michigan University (Mt. Pleasant, MI) and my Ph.D. in Human Genetics from the University of Michigan (Ann Arbor, MI). I joined Clemson University as an assistant professor in the department of Genetics and Biochemistry in January 2017.\r\n<h3><strong>Research<\/strong><\/h3>\r\nOur lab is interested in understanding the molecular mechanisms underlying genome instability in human cancers. Specifically, we study the role of the DNA repair pathway, homologous recombination, in repair of DNA damage caused by double strand break inducing chemotherapeutics and replication stress. This pathway prevents the accumulation of potentially detrimental mutations and protects genome stability. In addition, we are aiming to understand how DNA repair pathways function to protect replication forks in response to genotoxic stresses.\u00a0 Finally, we are interested in identifying and characterizing genetic interactions that may lead to novel chemotherapeutic treatments for cancers harboring defects in DNA repair pathways.\r\n<h3><strong>Publications<\/strong><\/h3>\r\nAbrams SR, Hawks AL, Evans JM, Famula TR, Mahaffey M, Johnson GS, <strong>Mason JM<\/strong> and <strong>Clark LA<\/strong>. 2020. Variants in\u00a0<em>FtsJ RNA 2'-O-Methyltransferase 3<\/em>\u00a0and\u00a0<em>Growth Hormone 1<\/em>\u00a0are associated with small body size and a dental anomaly in dogs. <em>Proc Natl Acad Sci USA.<\/em> <strong>117:<\/strong> 24929-24935. doi: 10.1073\/pnas.2009500117.","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[12],"tags":[],"class_list":["post-634","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-faculty"],"_links":{"self":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts\/634","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/comments?post=634"}],"version-history":[{"count":0,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts\/634\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/media\/635"}],"wp:attachment":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/media?parent=634"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/categories?post=634"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/tags?post=634"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}