{"id":1642,"date":"2024-12-02T08:58:32","date_gmt":"2024-12-02T13:58:32","guid":{"rendered":"https:\/\/scienceweb.clemson.edu\/chg\/?p=1642"},"modified":"2024-12-02T08:58:48","modified_gmt":"2024-12-02T13:58:48","slug":"tan-zhengzhi","status":"publish","type":"post","link":"https:\/\/scienceweb.clemson.edu\/ihg\/tan-zhengzhi\/","title":{"rendered":"Tan Zhengzhi"},"content":{"rendered":"<p><img decoding=\"async\" class=\"size-medium wp-image-1641 alignright lazyload\" title=\"person picture\" data-src=\"https:\/\/scienceweb.clemson.edu\/chg\/wp-content\/uploads\/sites\/4\/2024\/12\/person_picture-225x300.jpg\" alt=\"person picture\" width=\"225\" height=\"300\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 225px; --smush-placeholder-aspect-ratio: 225\/300;\" \/><\/p>\n<p>Graduate Student<\/p>\n<p>tzhengz@clemson.edu<\/p>\n<h3><strong>Biosketch<\/strong><\/h3>\n<p>I am a PhD student in Genetics and Biochemistry at Clemson University, focusing on integrating bioinformatics and artificial intelligence to advance genomic research. My work aims to bridge biology and computational science, unraveling complex genetic mechanisms and contributing to transformative discoveries in genomics.<\/p>\n<h3><strong>Research Interests<\/strong><\/h3>\n<p>My research lies at the intersection of bioinformatics and artificial intelligence, with a particular focus on single-cell analysis and the development of AI-driven tools for interpreting genomic data. I am especially intrigued by the potential of artificial intelligence to unlock new perspectives in DNA research, identifying hidden regulatory mechanisms and conserved genetic programs.<\/p>\n<h3><strong>Publications<\/strong><\/h3>\n<ol>\n<li><strong>Gene Fusion Detection and Characterization in Long-Read Cancer Transcriptome Sequencing Data with FusionSeeker<\/strong><br \/>\n<em>Cancer Research<\/em>, 2023. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36318117\/\">PubMed<\/a><\/li>\n<li><strong>Sesquiterpene Lactone Bigelovin Induces Apoptosis of Colon Cancer Cells Through Inducing IKK-\u03b2 Degradation and Suppressing Nuclear Factor Kappa B Activation<\/strong><br \/>\n<em>Anticancer Drugs<\/em>, 2021. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33929997\/\">PubMed<\/a><\/li>\n<li><strong>Loss of BRMS2 Induces Cell Growth Inhibition and Translation Capacity Reduction in Colorectal Cancer Cells<\/strong><br \/>\n<em>American Journal of Cancer Research<\/em>, 2021. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33791164\/\">PubMed<\/a><\/li>\n<\/ol>\n<h3><strong>Ongoing Projects<\/strong><\/h3>\n<ul>\n<li><strong>Using Deep Learning Models to Identify Conserved Regulatory Programs for Cross-Species Plant Single-Cell Analysis<\/strong><br \/>\nThis project applies advanced deep learning techniques to analyze and identify conserved regulatory elements within plant genomic data at the single-cell level, enhancing our understanding of gene expression and cellular function across different plant species.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Graduate Student tzhengz@clemson.edu Biosketch I am a PhD student in Genetics and Biochemistry at Clemson University, focusing on integrating bioinformatics and artificial intelligence to advance genomic research. My work aims to bridge biology and computational science, unraveling complex genetic mechanisms and contributing to transformative discoveries in genomics. Research Interests My research lies at the intersection [&hellip;]<\/p>\n","protected":false},"author":32,"featured_media":1641,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[14],"tags":[],"class_list":["post-1642","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-students"],"_links":{"self":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts\/1642","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/users\/32"}],"replies":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/comments?post=1642"}],"version-history":[{"count":0,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts\/1642\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/media\/1641"}],"wp:attachment":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/media?parent=1642"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/categories?post=1642"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/tags?post=1642"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}