Biosketch![\"alexis](\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\")
<\/strong><\/h2>\nDr. Alexis “Stocko” Stamatikos is currently a tenure-track assistant professor at Clemson University and has been in this position since January of 2019.\u00a0 Before joining Clemson University, Dr. Stamatikos received his PhD in nutritional sciences at Texas Tech University and completed a dietetic internship at Texas A&M University-Kingsville.\u00a0 Dr. Stamatikos also received postdoctoral training in vascular biology and gene therapy within the Department of Medicine, Division of Cardiology, at University of Washington.\u00a0 While at University of Washington, Dr. Stamatikos was initially supported by an NIH\/NHLBI-funded T32 Cardiovascular Research Training Program and then later awarded an American Heart Association (AHA) postdoctoral fellowship grant.\u00a0 Since becoming a PI at Clemson University, Dr. Stamatikos has received funding from NIH, AHA, and USDA.<\/p>\n
Research<\/strong><\/h2>\nAtherosclerosis is a disease caused by lipid accumulation within the arterial wall which can result in narrowing of the arteries.\u00a0 Atherosclerosis leads to more deaths worldwide than any other disease because atherosclerosis is the primary cause of both heart attacks and strokes.\u00a0 Although atherosclerosis has been extensively studied, the pathogenesis and pathophysiology of this disease are not entirely elucidated and treatments for atherosclerosis are only partially effective.\u00a0 Dr. Stamatikos and his laboratory are primarily focused on atherosclerosis research.\u00a0 Dr. Stamatikos’ research interests include identifying mechanisms that drive atherosclerosis and developing innovative atheroprotective therapeutics.\u00a0 A main research area of Dr. Stamatikos’ laboratory is assessing the impact of vascular inflammation and vessel wall cell cholesterol efflux on atherogenesis and atherosclerosis progression.\u00a0 Another major research area of the Stamatikos lab is the development of novel exosome\/lipoparticle-based anti-atherosclerotic therapies.<\/p>\n
Publications<\/strong><\/h2>\nHuang K, Jo H, Echesabal-Chen J, Stamatikos A.<\/strong> Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells. Metabolites.<\/em> 2021;11:640. (PMID: 34564456)<\/p>\nEsobi IC, Barksdale C, Heard-Tate C, Reigers Powell R, Bruce TF, Stamatikos A.<\/strong> MOVAS Cells: A Versatile Cell Line for Studying Vascular Smooth Muscle Cell Cholesterol Metabolism. Lipids.<\/em> 2021;56:413-422. (PMID: 33881166)<\/p>\nBi L, Wacker BK,\u00a0Stamatikos A,<\/strong> Sethuraman M, Komandur K, Dichek DA. Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta. Arterioscler Thromb Vasc Biol.<\/em> 2021;41:1149-1155. (PMID: 33297756)<\/p>\nStamatikos A,<\/strong> Knight E, Vojtech L, Bi L, Wacker BK, Tang C, Dichek DA. Exosome-Mediated Transfer of Anti-miR-33a-5p from Transduced Endothelial Cells Enhances Macrophage and Vascular Smooth Muscle Cell Cholesterol Efflux. Hum Gene Ther.<\/em> 2020;31:219-232. (PMID: 31842627)<\/p>\nStamatikos A,<\/strong> Dronadula N, Ng P, Palmer D, Knight E, Wacker B, Tang C, Kim F, Dichek DA. ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation. Hum Gene Ther.<\/em> 2019;30:236-248. (PMID: 30079772)<\/p>\nWacker BK, Dronadula N, Bi L, Stamatikos A<\/strong>,<\/strong> Dichek DA. Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits. Arterioscler Thromb Vasc Biol.<\/em> 2018;38:206-217. (PMID: 29122817)<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
Assistant Professor, Department of Food, Nutrition, and Packaging Sciences Biosketch Dr. Alexis “Stocko” Stamatikos is currently a tenure-track assistant professor at Clemson University and has been in this position since January of 2019.\u00a0 Before joining Clemson University, Dr. Stamatikos received his PhD in nutritional sciences at Texas Tech University and completed a dietetic internship at […]<\/p>\n","protected":false},"author":13,"featured_media":1077,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"Assistant Professor, Department of Food, Nutrition, and Packaging Sciences<\/strong>\r\nBiosketch![\"alexis](\"https:\/\/scienceweb.clemson.edu\/chg\/wp-content\/uploads\/sites\/4\/2021\/10\/alexis-stamatikos-e1634054713122.png\")
<\/strong><\/h3>\r\nDr. Alexis \"Stocko\" Stamatikos is currently a tenure-track assistant professor at Clemson University and has been in this position since January of 2019.\u00a0 Before joining Clemson University, Dr. Stamatikos received his PhD in nutritional sciences at Texas Tech University and completed a dietetic internship at Texas A&M University-Kingsville.\u00a0 Dr. Stamatikos also received postdoctoral training in vascular biology and gene therapy within the Department of Medicine, Division of Cardiology, at University of Washington.\u00a0 While at University of Washington, Dr. Stamatikos was initially supported by an NIH\/NHLBI-funded T32 Cardiovascular Research Training Program and then later awarded an American Heart Association (AHA) postdoctoral fellowship grant.\u00a0 Since becoming a PI at Clemson University, Dr. Stamatikos has received funding from NIH, AHA, and USDA.\r\nResearch<\/strong><\/h3>\r\nAtherosclerosis is a disease caused by lipid accumulation within the arterial wall which can result in narrowing of the arteries.\u00a0 Atherosclerosis leads to more deaths worldwide than any other disease because atherosclerosis is the primary cause of both heart attacks and strokes.\u00a0 Although atherosclerosis has been extensively studied, the pathogenesis and pathophysiology of this disease are not entirely elucidated and treatments for atherosclerosis are only partially effective.\u00a0 Dr. Stamatikos and his laboratory are primarily focused on atherosclerosis research.\u00a0 Dr. Stamatikos' research interests include identifying mechanisms that drive atherosclerosis and developing innovative atheroprotective therapeutics.\u00a0 A main research area of Dr. Stamatikos' laboratory is assessing the impact of vascular inflammation and vessel wall cell cholesterol efflux on atherogenesis and atherosclerosis progression.\u00a0 Another major research area of the Stamatikos lab is the development of novel exosome\/lipoparticle-based anti-atherosclerotic therapies.\r\nPublications<\/strong><\/h3>\r\nHuang K, Jo H, Echesabal-Chen J, Stamatikos A.<\/strong> Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells. Metabolites.<\/em> 2021;11:640. (PMID: 34564456)\r\n\r\nEsobi IC, Barksdale C, Heard-Tate C, Reigers Powell R, Bruce TF, Stamatikos A.<\/strong> MOVAS Cells: A Versatile Cell Line for Studying Vascular Smooth Muscle Cell Cholesterol Metabolism. Lipids.<\/em> 2021;56:413-422. (PMID: 33881166)\r\n\r\nBi L, Wacker BK,\u00a0Stamatikos A,<\/strong> Sethuraman M, Komandur K, Dichek DA. Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta. Arterioscler Thromb Vasc Biol.<\/em> 2021;41:1149-1155. (PMID: 33297756)\r\n\r\nStamatikos A,<\/strong> Knight E, Vojtech L, Bi L, Wacker BK, Tang C, Dichek DA. Exosome-Mediated Transfer of Anti-miR-33a-5p from Transduced Endothelial Cells Enhances Macrophage and Vascular Smooth Muscle Cell Cholesterol Efflux. Hum Gene Ther.<\/em> 2020;31:219-232. (PMID: 31842627)\r\n\r\nStamatikos A,<\/strong> Dronadula N, Ng P, Palmer D, Knight E, Wacker B, Tang C, Kim F, Dichek DA. ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation. Hum Gene Ther.<\/em> 2019;30:236-248. (PMID: 30079772)\r\n\r\nWacker BK, Dronadula N, Bi L, Stamatikos A<\/strong>,<\/strong> Dichek DA. Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits. Arterioscler Thromb Vasc Biol.<\/em> 2018;38:206-217. (PMID: 29122817)","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[12],"tags":[],"class_list":["post-1076","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-faculty"],"_links":{"self":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts\/1076","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/comments?post=1076"}],"version-history":[{"count":0,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts\/1076\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/media\/1077"}],"wp:attachment":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/media?parent=1076"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/categories?post=1076"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/tags?post=1076"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Atherosclerosis is a disease caused by lipid accumulation within the arterial wall which can result in narrowing of the arteries.\u00a0 Atherosclerosis leads to more deaths worldwide than any other disease because atherosclerosis is the primary cause of both heart attacks and strokes.\u00a0 Although atherosclerosis has been extensively studied, the pathogenesis and pathophysiology of this disease are not entirely elucidated and treatments for atherosclerosis are only partially effective.\u00a0 Dr. Stamatikos and his laboratory are primarily focused on atherosclerosis research.\u00a0 Dr. Stamatikos’ research interests include identifying mechanisms that drive atherosclerosis and developing innovative atheroprotective therapeutics.\u00a0 A main research area of Dr. Stamatikos’ laboratory is assessing the impact of vascular inflammation and vessel wall cell cholesterol efflux on atherogenesis and atherosclerosis progression.\u00a0 Another major research area of the Stamatikos lab is the development of novel exosome\/lipoparticle-based anti-atherosclerotic therapies.<\/p>\n
Publications<\/strong><\/h2>\nHuang K, Jo H, Echesabal-Chen J, Stamatikos A.<\/strong> Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells. Metabolites.<\/em> 2021;11:640. (PMID: 34564456)<\/p>\nEsobi IC, Barksdale C, Heard-Tate C, Reigers Powell R, Bruce TF, Stamatikos A.<\/strong> MOVAS Cells: A Versatile Cell Line for Studying Vascular Smooth Muscle Cell Cholesterol Metabolism. Lipids.<\/em> 2021;56:413-422. (PMID: 33881166)<\/p>\nBi L, Wacker BK,\u00a0Stamatikos A,<\/strong> Sethuraman M, Komandur K, Dichek DA. Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta. Arterioscler Thromb Vasc Biol.<\/em> 2021;41:1149-1155. (PMID: 33297756)<\/p>\nStamatikos A,<\/strong> Knight E, Vojtech L, Bi L, Wacker BK, Tang C, Dichek DA. Exosome-Mediated Transfer of Anti-miR-33a-5p from Transduced Endothelial Cells Enhances Macrophage and Vascular Smooth Muscle Cell Cholesterol Efflux. Hum Gene Ther.<\/em> 2020;31:219-232. (PMID: 31842627)<\/p>\nStamatikos A,<\/strong> Dronadula N, Ng P, Palmer D, Knight E, Wacker B, Tang C, Kim F, Dichek DA. ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation. Hum Gene Ther.<\/em> 2019;30:236-248. (PMID: 30079772)<\/p>\nWacker BK, Dronadula N, Bi L, Stamatikos A<\/strong>,<\/strong> Dichek DA. Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits. Arterioscler Thromb Vasc Biol.<\/em> 2018;38:206-217. (PMID: 29122817)<\/p>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"
Assistant Professor, Department of Food, Nutrition, and Packaging Sciences Biosketch Dr. Alexis “Stocko” Stamatikos is currently a tenure-track assistant professor at Clemson University and has been in this position since January of 2019.\u00a0 Before joining Clemson University, Dr. Stamatikos received his PhD in nutritional sciences at Texas Tech University and completed a dietetic internship at […]<\/p>\n","protected":false},"author":13,"featured_media":1077,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"Assistant Professor, Department of Food, Nutrition, and Packaging Sciences<\/strong>\r\nBiosketch<\/strong><\/h3>\r\nDr. Alexis \"Stocko\" Stamatikos is currently a tenure-track assistant professor at Clemson University and has been in this position since January of 2019.\u00a0 Before joining Clemson University, Dr. Stamatikos received his PhD in nutritional sciences at Texas Tech University and completed a dietetic internship at Texas A&M University-Kingsville.\u00a0 Dr. Stamatikos also received postdoctoral training in vascular biology and gene therapy within the Department of Medicine, Division of Cardiology, at University of Washington.\u00a0 While at University of Washington, Dr. Stamatikos was initially supported by an NIH\/NHLBI-funded T32 Cardiovascular Research Training Program and then later awarded an American Heart Association (AHA) postdoctoral fellowship grant.\u00a0 Since becoming a PI at Clemson University, Dr. Stamatikos has received funding from NIH, AHA, and USDA.\r\nResearch<\/strong><\/h3>\r\nAtherosclerosis is a disease caused by lipid accumulation within the arterial wall which can result in narrowing of the arteries.\u00a0 Atherosclerosis leads to more deaths worldwide than any other disease because atherosclerosis is the primary cause of both heart attacks and strokes.\u00a0 Although atherosclerosis has been extensively studied, the pathogenesis and pathophysiology of this disease are not entirely elucidated and treatments for atherosclerosis are only partially effective.\u00a0 Dr. Stamatikos and his laboratory are primarily focused on atherosclerosis research.\u00a0 Dr. Stamatikos' research interests include identifying mechanisms that drive atherosclerosis and developing innovative atheroprotective therapeutics.\u00a0 A main research area of Dr. Stamatikos' laboratory is assessing the impact of vascular inflammation and vessel wall cell cholesterol efflux on atherogenesis and atherosclerosis progression.\u00a0 Another major research area of the Stamatikos lab is the development of novel exosome\/lipoparticle-based anti-atherosclerotic therapies.\r\nPublications<\/strong><\/h3>\r\nHuang K, Jo H, Echesabal-Chen J, Stamatikos A.<\/strong> Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells. Metabolites.<\/em> 2021;11:640. (PMID: 34564456)\r\n\r\nEsobi IC, Barksdale C, Heard-Tate C, Reigers Powell R, Bruce TF, Stamatikos A.<\/strong> MOVAS Cells: A Versatile Cell Line for Studying Vascular Smooth Muscle Cell Cholesterol Metabolism. Lipids.<\/em> 2021;56:413-422. (PMID: 33881166)\r\n\r\nBi L, Wacker BK,\u00a0Stamatikos A,<\/strong> Sethuraman M, Komandur K, Dichek DA. Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta. Arterioscler Thromb Vasc Biol.<\/em> 2021;41:1149-1155. (PMID: 33297756)\r\n\r\nStamatikos A,<\/strong> Knight E, Vojtech L, Bi L, Wacker BK, Tang C, Dichek DA. Exosome-Mediated Transfer of Anti-miR-33a-5p from Transduced Endothelial Cells Enhances Macrophage and Vascular Smooth Muscle Cell Cholesterol Efflux. Hum Gene Ther.<\/em> 2020;31:219-232. (PMID: 31842627)\r\n\r\nStamatikos A,<\/strong> Dronadula N, Ng P, Palmer D, Knight E, Wacker B, Tang C, Kim F, Dichek DA. ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation. Hum Gene Ther.<\/em> 2019;30:236-248. (PMID: 30079772)\r\n\r\nWacker BK, Dronadula N, Bi L, Stamatikos A<\/strong>,<\/strong> Dichek DA. Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits. Arterioscler Thromb Vasc Biol.<\/em> 2018;38:206-217. (PMID: 29122817)","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[12],"tags":[],"class_list":["post-1076","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-faculty"],"_links":{"self":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts\/1076","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/comments?post=1076"}],"version-history":[{"count":0,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts\/1076\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/media\/1077"}],"wp:attachment":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/media?parent=1076"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/categories?post=1076"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/tags?post=1076"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Esobi IC, Barksdale C, Heard-Tate C, Reigers Powell R, Bruce TF, Stamatikos A.<\/strong> MOVAS Cells: A Versatile Cell Line for Studying Vascular Smooth Muscle Cell Cholesterol Metabolism. Lipids.<\/em> 2021;56:413-422. (PMID: 33881166)<\/p>\n Bi L, Wacker BK,\u00a0Stamatikos A,<\/strong> Sethuraman M, Komandur K, Dichek DA. Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta. Arterioscler Thromb Vasc Biol.<\/em> 2021;41:1149-1155. (PMID: 33297756)<\/p>\n Stamatikos A,<\/strong> Knight E, Vojtech L, Bi L, Wacker BK, Tang C, Dichek DA. Exosome-Mediated Transfer of Anti-miR-33a-5p from Transduced Endothelial Cells Enhances Macrophage and Vascular Smooth Muscle Cell Cholesterol Efflux. Hum Gene Ther.<\/em> 2020;31:219-232. (PMID: 31842627)<\/p>\n Stamatikos A,<\/strong> Dronadula N, Ng P, Palmer D, Knight E, Wacker B, Tang C, Kim F, Dichek DA. ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation. Hum Gene Ther.<\/em> 2019;30:236-248. (PMID: 30079772)<\/p>\n Wacker BK, Dronadula N, Bi L, Stamatikos A<\/strong>,<\/strong> Dichek DA. Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits. Arterioscler Thromb Vasc Biol.<\/em> 2018;38:206-217. (PMID: 29122817)<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Assistant Professor, Department of Food, Nutrition, and Packaging Sciences Biosketch Dr. Alexis “Stocko” Stamatikos is currently a tenure-track assistant professor at Clemson University and has been in this position since January of 2019.\u00a0 Before joining Clemson University, Dr. Stamatikos received his PhD in nutritional sciences at Texas Tech University and completed a dietetic internship at […]<\/p>\n","protected":false},"author":13,"featured_media":1077,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"Assistant Professor, Department of Food, Nutrition, and Packaging Sciences<\/strong>\r\nBiosketch
<\/strong><\/h3>\r\nDr. Alexis \"Stocko\" Stamatikos is currently a tenure-track assistant professor at Clemson University and has been in this position since January of 2019.\u00a0 Before joining Clemson University, Dr. Stamatikos received his PhD in nutritional sciences at Texas Tech University and completed a dietetic internship at Texas A&M University-Kingsville.\u00a0 Dr. Stamatikos also received postdoctoral training in vascular biology and gene therapy within the Department of Medicine, Division of Cardiology, at University of Washington.\u00a0 While at University of Washington, Dr. Stamatikos was initially supported by an NIH\/NHLBI-funded T32 Cardiovascular Research Training Program and then later awarded an American Heart Association (AHA) postdoctoral fellowship grant.\u00a0 Since becoming a PI at Clemson University, Dr. Stamatikos has received funding from NIH, AHA, and USDA.\r\nResearch<\/strong><\/h3>\r\nAtherosclerosis is a disease caused by lipid accumulation within the arterial wall which can result in narrowing of the arteries.\u00a0 Atherosclerosis leads to more deaths worldwide than any other disease because atherosclerosis is the primary cause of both heart attacks and strokes.\u00a0 Although atherosclerosis has been extensively studied, the pathogenesis and pathophysiology of this disease are not entirely elucidated and treatments for atherosclerosis are only partially effective.\u00a0 Dr. Stamatikos and his laboratory are primarily focused on atherosclerosis research.\u00a0 Dr. Stamatikos' research interests include identifying mechanisms that drive atherosclerosis and developing innovative atheroprotective therapeutics.\u00a0 A main research area of Dr. Stamatikos' laboratory is assessing the impact of vascular inflammation and vessel wall cell cholesterol efflux on atherogenesis and atherosclerosis progression.\u00a0 Another major research area of the Stamatikos lab is the development of novel exosome\/lipoparticle-based anti-atherosclerotic therapies.\r\n
Publications<\/strong><\/h3>\r\nHuang K, Jo H, Echesabal-Chen J, Stamatikos A.<\/strong> Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells. Metabolites.<\/em> 2021;11:640. (PMID: 34564456)\r\n\r\nEsobi IC, Barksdale C, Heard-Tate C, Reigers Powell R, Bruce TF, Stamatikos A.<\/strong> MOVAS Cells: A Versatile Cell Line for Studying Vascular Smooth Muscle Cell Cholesterol Metabolism. Lipids.<\/em> 2021;56:413-422. (PMID: 33881166)\r\n\r\nBi L, Wacker BK,\u00a0Stamatikos A,<\/strong> Sethuraman M, Komandur K, Dichek DA. Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta. Arterioscler Thromb Vasc Biol.<\/em> 2021;41:1149-1155. (PMID: 33297756)\r\n\r\nStamatikos A,<\/strong> Knight E, Vojtech L, Bi L, Wacker BK, Tang C, Dichek DA. Exosome-Mediated Transfer of Anti-miR-33a-5p from Transduced Endothelial Cells Enhances Macrophage and Vascular Smooth Muscle Cell Cholesterol Efflux. Hum Gene Ther.<\/em> 2020;31:219-232. (PMID: 31842627)\r\n\r\nStamatikos A,<\/strong> Dronadula N, Ng P, Palmer D, Knight E, Wacker B, Tang C, Kim F, Dichek DA. ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation. Hum Gene Ther.<\/em> 2019;30:236-248. (PMID: 30079772)\r\n\r\nWacker BK, Dronadula N, Bi L, Stamatikos A<\/strong>,<\/strong> Dichek DA. Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits. Arterioscler Thromb Vasc Biol.<\/em> 2018;38:206-217. (PMID: 29122817)","_et_gb_content_width":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[12],"tags":[],"class_list":["post-1076","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-faculty"],"_links":{"self":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts\/1076","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/comments?post=1076"}],"version-history":[{"count":0,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/posts\/1076\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/media\/1077"}],"wp:attachment":[{"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/media?parent=1076"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/categories?post=1076"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/ihg\/wp-json\/wp\/v2\/tags?post=1076"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}