{"id":1741,"date":"2025-06-06T17:07:04","date_gmt":"2025-06-06T21:07:04","guid":{"rendered":"https:\/\/scienceweb.clemson.edu\/chg\/?page_id=1741"},"modified":"2026-02-06T14:07:20","modified_gmt":"2026-02-06T19:07:20","slug":"genomics-core","status":"publish","type":"page","link":"https:\/\/scienceweb.clemson.edu\/ihg\/research-cores\/genomics-core\/","title":{"rendered":"Genomics Core"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;on||&#8221; admin_label=&#8221;Hero&#8221; _builder_version=&#8221;4.27.4&#8243; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_stops=&#8221;rgba(71,74,182,0.27) 0%|rgba(50,46,102,0.6) 100%&#8221; background_color_gradient_start=&#8221;rgba(71,74,182,0.27)&#8221; background_color_gradient_end=&#8221;rgba(50,46,102,0.6)&#8221; background_image=&#8221;https:\/\/scienceweb.clemson.edu\/chg\/wp-content\/uploads\/sites\/4\/2025\/07\/facility2.jpg&#8221; background_blend=&#8221;overlay&#8221; custom_padding=&#8221;|0px||0px&#8221; 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header_font_size=&#8221;48px&#8221; header_line_height=&#8221;1.2em&#8221; background_layout=&#8221;dark&#8221; custom_padding=&#8221;|||&#8221; header_font_size_last_edited=&#8221;off|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>IHG Genomics Core<\/h1>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.5&#8243; text_font=&#8221;&#8211;et_global_body_font||||||||&#8221; text_text_color=&#8221;#ffffff&#8221; text_font_size=&#8221;20px&#8221; text_line_height=&#8221;1.2em&#8221; custom_padding=&#8221;||0px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">The Genomics Core delivers end-to-end genomics support using state-of-the-art sequencing technologies, including the Illumina NovaSeq X+, PacBio Revio, ONT PromethION P2 Integrated, and 10x Genomics Chromium iX. Our expert staff partner with investigators from study design through data generation to support a wide range of applications, including whole-genome sequencing, RNA-seq, ATAC-seq, single-cell, and other high-throughput genomics assays. We also offer wet lab training courses and seminars to give users hands-on experience.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; disabled_on=&#8221;|on|on&#8221; admin_label=&#8221;Hero&#8221; _builder_version=&#8221;4.27.4&#8243; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_stops=&#8221;rgba(71,74,182,0.27) 0%|#322e66 100%&#8221; background_color_gradient_start=&#8221;rgba(71,74,182,0.27)&#8221; background_color_gradient_end=&#8221;#322e66&#8243; background_image=&#8221;https:\/\/scienceweb.clemson.edu\/chg\/wp-content\/uploads\/sites\/4\/2025\/07\/facility2.jpg&#8221; background_position=&#8221;top_center&#8221; background_blend=&#8221;overlay&#8221; custom_padding=&#8221;|0px||0px&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;top&#8221; animation_intensity_slide=&#8221;2%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; 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background_layout=&#8221;dark&#8221; custom_padding=&#8221;|||&#8221; header_font_size_last_edited=&#8221;off|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>IHG Genomics Core<\/h1>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.27.5&#8243; text_text_color=&#8221;#ffffff&#8221; text_font_size=&#8221;14px&#8221; text_line_height=&#8221;1.2em&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span class=\"OYPEnA font-feature-liga-off font-feature-clig-off font-feature-calt-off text-decoration-none text-strikethrough-none\">The Genomics Core delivers end-to-end genomics support using state-of-the-art sequencing technologies, including the Illumina NovaSeq X+, PacBio Revio, ONT PromethION P2 Integrated, and 10x Genomics Chromium iX. Our expert staff partner with investigators from study design through data generation to support a wide range of applications, including whole-genome sequencing, RNA-seq, ATAC-seq, single-cell, and other high-throughput genomics assays. We also offer wet lab training courses and seminars to give users hands-on experience.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Courses&#8221; _builder_version=&#8221;4.27.4&#8243; custom_padding=&#8221;0px|0px|0px|0px||&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;2_3,1_3&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/scienceweb.clemson.edu\/ihg\/wp-content\/uploads\/sites\/4\/2026\/02\/IMG_9170-scaled-1-1.jpg&#8221; alt=&#8221;A woman with dark hair and in glasses dressed in black standing next to a purple banner that says Clemson Center for Human Genetics&#8221; title_text=&#8221;Genomics Core Staff&#8221; _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;|0px||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.5&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;&#8211;et_global_body_font||||||||&#8221; text_font_size=&#8221;20px&#8221; header_font_size=&#8221;37px&#8221; header_2_font=&#8221;&#8211;et_global_heading_font||||||||&#8221; text_orientation=&#8221;center&#8221; min_height=&#8221;220.9px&#8221; custom_margin=&#8221;204px|||-90px||&#8221; custom_padding=&#8221;||0px|||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<h2><strong>Meet the Genomics Core!<\/strong><\/h2>\n<p style=\"text-align: left\">Ms. Kaitlyn Williams, M.S. (pictured left) directs the Clemson University Institute for Human Genetics Genomics Core. She hold a total of 10 years of molecular wet lab experience!<\/p>\n<p style=\"text-align: left\">Our Core provides comprehensive services for every stage of next-generation sequencing, including extraction, library preparation, and quality control. 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Ideal for applications such as whole-genome sequencing, transcriptome analysis, and structural variant detection, the Revio can generate up to 1.4 terabases of data per day\u2014supporting up to 1,300 human genomes per year at 30\u00d7 coverage.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;Illumina NovaSeq X+&#8221; image=&#8221;https:\/\/scienceweb.clemson.edu\/chg\/wp-content\/uploads\/sites\/4\/2025\/06\/IlluminaRESIZED-1.png&#8221; alt=&#8221;White\/silver laboratory instrument with rectangular housing, digital display screen on top showing time readings, and blue illuminated oval window in the center of the front panel.*&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_level=&#8221;h3&#8243; header_text_align=&#8221;center&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center\">The Genomics Core offers sequencing services using the Illumina NovaSeq X+, a state-of-the-art high-throughput platform capable of generating up to 16 Tb of data in under 48 hours. This system delivers exceptional accuracy, scalability, and cost-efficiency, making it ideal for large-scale projects such as whole-genome, single-cell, and transcriptome sequencing. Let us help power your next big discovery.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;ONT PromethION 2 Integrated (P2i)&#8221; image=&#8221;https:\/\/scienceweb.clemson.edu\/chg\/wp-content\/uploads\/sites\/4\/2025\/06\/NANOPORERESIZED.png&#8221; alt=&#8221;Black Oxford Nanopore PromethION 2 with front mesh panel, tilted touchscreen showing circular data, and logo on the side.&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_level=&#8221;h3&#8243; header_text_align=&#8221;center&#8221; text_orientation=&#8221;center&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>The Genomics Core offers access to the Oxford Nanopore PromethION 2 Integrated (P2i), a compact benchtop sequencer built for medium-to-high-throughput projects. 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This advanced system provides high-resolution sizing and quantification of DNA and RNA, including total RNA, genomic DNA, and NGS libraries. With reliable quality metrics like RQN and GQN, it ensures accurate and consistent sample assessment for your research needs.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_blurb title=&#8221;Opentrons Flex&#8221; image=&#8221;https:\/\/scienceweb.clemson.edu\/chg\/wp-content\/uploads\/sites\/4\/2025\/06\/OTFLEX.png&#8221; alt=&#8221;Black and gray Opentrons Flex robot with a cubic frame, transparent panels, visible pipetting head, and blue module spots on the deck.<br \/>\n&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; header_level=&#8221;h3&#8243; header_font=&#8221;&#8211;et_global_heading_font||||||||&#8221; header_text_align=&#8221;center&#8221; body_font=&#8221;&#8211;et_global_body_font||||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center\">The Genomics Core now offers advanced automation capabilities with our in-house Opentrons Flex liquid handling robot. In addition to supporting high-throughput genomics workflows, the Flex is equipped to shear high molecular weight (HMW) DNA\u2014ideal for preparing samples for long-read sequencing. This enables faster, more consistent processing for a wide range of applications.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Services&#8221; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;5138c454-be54-4233-bd3b-f8e6a8747976&#8243; custom_margin=&#8221;|auto|-10px|auto|false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.18.0&#8243; _module_preset=&#8221;73121f80-a3ef-4484-8763-c3f18e3c56d2&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_heading title=&#8221;Comprehensive Genetic Services&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;c33f07d9-41e0-421a-8799-5799df695cce&#8221; title_level=&#8221;h2&#8243; title_font=&#8221;&#8211;et_global_heading_font|IBM Plex Sans Condensed_weight|||||||&#8221; 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