{"id":1748,"date":"2026-01-27T14:25:51","date_gmt":"2026-01-27T19:25:51","guid":{"rendered":"https:\/\/scienceweb.clemson.edu\/epic\/?page_id=1748"},"modified":"2026-01-27T14:25:57","modified_gmt":"2026-01-27T19:25:57","slug":"lesly-temesvari","status":"publish","type":"page","link":"https:\/\/scienceweb.clemson.edu\/epic\/about\/people\/lesly-temesvari\/","title":{"rendered":"Lesly Temesvari"},"content":{"rendered":"

[et_pb_section fb_built=”1″ admin_label=”section” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ admin_label=”row” _builder_version=”4.16″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_sidebar _builder_version=”4.27.0″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_sidebar][et_pb_image src=”https:\/\/scienceweb.clemson.edu\/epic\/wp-content\/uploads\/sites\/13\/2026\/01\/LT-headshot.jpg” alt=”Lesly Temesvari headshot” title_text=”Lesly Temesvari ” align=”center” _builder_version=”4.27.5″ _module_preset=”default” height=”500px” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″][\/et_pb_image][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Name:<\/strong> Lesly Temesvari <\/p>\n

Title:<\/strong> Alumni Distinguished Professor and Associate Chair<\/p>\n

Department:<\/strong> Biological Sciences<\/p>\n

Email:<\/strong> ltemesv@clemson.edu<\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.27.5″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]Biosketch:<\/strong>
\nDr. Temesvari completed a BS in Microbiology and Immunology from McGill University (Montreal, Canada) and a Ph.D. in Biological Sciences from the University of Windsor (Windsor, Canada). After completing a post-doctoral fellowship and LSU Health Sciences Center (Shreveport, LA) she joined the faculty at Clemson University<\/p>\n

 <\/p>\n

Research Summary:<\/strong>
\nThe overall goal of the Temesvari laboratory is to understand the molecular mechanisms regulating a virulence in several pathogenic amoebae, Entamoeba histolytica and Acanthamoeba castellanii. These parasites causes amoebic dysentery and liver abscess) and keratitis, respectively. The Temesvari laboratory focuses on parasite-host interactions, the stress response in the parasite, vesicle trafficking, lipid rafts and drug-repurposing.<\/p>\n

 <\/p>\n

Selected Publications:<\/strong>
\n2022 Walters, H.A., Welter, B.H., Moss, H.C., Villano, M.A., Orobio-Hurtado, R., Sullivan, W.J. Jr., Temesvari, L.A. Eukaryotic Initiation Factor 2-alpha Kinases Regulate Virulence Functions, Stage Conversion, and the Stress Response in Entamoeba invadens. mSphere. 7(3):e0013122. doi: 10.1128\/msphere.00131-22.<\/p>\n

2021 Karambizi, N.U., McMahan, C.S., Blue, C.N., and Temesvari, L.A. Global estimated Disability-Adjusted Life-Years (DALYs) of diarrheal diseases: A systematic analysis of data from 28 years of the global burden of disease study. PLoS One 16(10):e0259077. doi: 10.1371\/journal.pone.0259077.<\/p>\n

2021 Walters, H.A., Welter, B.H., Orobio-Hurtado, R., Moss, H.C., Villano, M.A., Sullivan, W.J., Jr., and Temesvari, L.A. EiIF2K-A, a eukaryotic initiation factor 2-alpha kinase, regulates virulence functions, stageconversion, and the stress response in Entamoeba invadens. Revising for PLoS Pathogens (IF=6.218)<\/p>\n

2020 Welter B.H., Walters H,A, and Temesvari L.A. Reduced expression of a rhomboid protease, EhROM1, correlates with changes in the submembrane distribution and size of the Gal\/GalNAc lectin subunits in the human protozoan parasite, Entamoeba histolytica. PLoS ONE 15(3): e0219870. https:\/\/doi.org\/10.1371\/journal.pone.0219870 (IF=2.776)[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Name: Lesly Temesvari Title: Alumni Distinguished Professor and Associate Chair Department: Biological Sciences Email: ltemesv@clemson.edu Biosketch: Dr. Temesvari completed a BS in Microbiology and Immunology from McGill University (Montreal, Canada) and a Ph.D. in Biological Sciences from the University of Windsor (Windsor, Canada). After completing a post-doctoral fellowship and LSU Health Sciences Center (Shreveport, LA) […]<\/p>\n","protected":false},"author":34,"featured_media":0,"parent":1252,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-1748","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/scienceweb.clemson.edu\/epic\/wp-json\/wp\/v2\/pages\/1748","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scienceweb.clemson.edu\/epic\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/scienceweb.clemson.edu\/epic\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/epic\/wp-json\/wp\/v2\/users\/34"}],"replies":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/epic\/wp-json\/wp\/v2\/comments?post=1748"}],"version-history":[{"count":0,"href":"https:\/\/scienceweb.clemson.edu\/epic\/wp-json\/wp\/v2\/pages\/1748\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/scienceweb.clemson.edu\/epic\/wp-json\/wp\/v2\/pages\/1252"}],"wp:attachment":[{"href":"https:\/\/scienceweb.clemson.edu\/epic\/wp-json\/wp\/v2\/media?parent=1748"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}