Graduate Student
tzhengz@clemson.edu
Biosketch
I am a PhD student in Genetics and Biochemistry at Clemson University, focusing on integrating bioinformatics and artificial intelligence to advance genomic research. My work aims to bridge biology and computational science, unraveling complex genetic mechanisms and contributing to transformative discoveries in genomics.
Research Interests
My research lies at the intersection of bioinformatics and artificial intelligence, with a particular focus on single-cell analysis and the development of AI-driven tools for interpreting genomic data. I am especially intrigued by the potential of artificial intelligence to unlock new perspectives in DNA research, identifying hidden regulatory mechanisms and conserved genetic programs.
Publications
- Gene Fusion Detection and Characterization in Long-Read Cancer Transcriptome Sequencing Data with FusionSeeker
Cancer Research, 2023. PubMed - Sesquiterpene Lactone Bigelovin Induces Apoptosis of Colon Cancer Cells Through Inducing IKK-β Degradation and Suppressing Nuclear Factor Kappa B Activation
Anticancer Drugs, 2021. PubMed - Loss of BRMS2 Induces Cell Growth Inhibition and Translation Capacity Reduction in Colorectal Cancer Cells
American Journal of Cancer Research, 2021. PubMed
Ongoing Projects
- Using Deep Learning Models to Identify Conserved Regulatory Programs for Cross-Species Plant Single-Cell Analysis
This project applies advanced deep learning techniques to analyze and identify conserved regulatory elements within plant genomic data at the single-cell level, enhancing our understanding of gene expression and cellular function across different plant species.