Graduate Student
khowe2@clemson.edu
Bio Sketch
I am originally from Northborough Massachusetts. I moved down to Macon, Georgia to attend Mercer University where I earned a B.S. in Biochemistry and Molecular Biology. While I was there, I worked on research teams under Dr. Linda Hensel, Dr. Amy Wiles and Dr. Adam Keifer. The main research projects focused on testing novel compounds and their ability to decrease the production of biofilm in different strains of bacteria. After graduating, I worked as a research technologist for two years under Dr. Mark Yarchoan in the GI oncology department at Johns Hopkins University. While I was there, I assisted several post-docs and grad students on topics including understanding secondary resistance to immunotherapy, cytokine profiling, and organoid development.
Research Interests
I am joining Dr. Tara Doucet-O’Hare’s lab and I will be working on neurodegeneration and repetitive elements in the human genome.
Publications
- Brown ST, Hasan KM, Moody KH, Loving DC, Howe KE, Dawson AG, Drace K, Hugdahl JD, Seney CS, Vega CM, Fernandez LE, Kiefer AM. Method for mapping Hg0 emissions from gold shops in artisanal and small-scale gold mining communities. MethodsX. 2020 Sep 9;7:101060. doi: 10.1016/j.mex.2020.101060. PMID: 32995311; PMCID:
- Kao C, Charmsaz S, Alden SL, Brancati M, Li HL, Balaji A, Munjal K, Howe K, Mitchell S, Griffin E, Nakazawa M, Tsai H, Danilova L, Thoburn C, Gizzi J, Hernandez A, Gross N, Coyne E, Shin S, Durham J, Christmas B, Konig MF, Lipson EJ, Naidoo J, Cappelli LC, Pabani A, Ged Y, Baretti M, Brahmer J, Hoffman-Censits J, Seiwert TY, Garonce-Hediger R, Guha A, Bansal S, Tang L, Jaffee E, Chandler GS, Mohindra R, Ho WJ, Yarchoan M.Th17 and Th2 signatures predict symptomatic irAEs in patients with solid tumors treated with immunotherapy. [Manuscript under review at Journal of Clinical Investigation].
- Shu DH, Ho WJ, Kagohara LT, Girgis A, Shin SM, Danilova L, Lee JW, Sidiropoulos DN, Mitchell S, Munjal K, Howe K, Bendinelli KJ, Qi H, Mo G, Montagne J, Leatherman JM, Lopez-Vidal TY, Zhu Q, Huff A, Yuan X, Hernandez A, Coyne EM, Zaidi N, Zabransky DJ, Engle L, Ogurtsova A, Baretti M, Laheru D, Durham J, Wang H, Anders R, Jaffee EM, Fertig EJ, Yarchoan M. Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma treated with neoadjuvant immune checkpoint blockade. bioRxiv 10.16.562104; doi: 10.1101/2023.10.16.562104 [Manuscript under review at Nature Immunology].